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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff4bbf2b8ca30b91962bfc4a6343614f74b1c4db45898d3477e9b12e8e5098f' 
  AND token = 'Cd3EClpzBNQeBBLhaSqOpL2wgeCdrcM9DCGry2ZfbCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}