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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd3c1f7153fe99aec10219efb5e40f91640466827ad2f626d5a76da4fccc725' 
  AND token = 'iGEiJPmpQIO91rYqp0lQAZK9y0U5BHNOiaqf4PYwy4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}