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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e121e3f72ea1f282decebe166eaa7bad1ae72235c93b6b9d558d0351c4ffb37' 
  AND token = '3tqjKE+Ihh+6v1a+mkVJWY0y2ZRwSWAAUGvu2hjIIRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}