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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '897e5a22594ffb02d1ca59b14b2b787c9e0295e556bf50c68dbfe8873ace96c2' 
  AND token = '2HVwE5pdngf11ZlgbizwLts4W392fYt2WFAj44QVxjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}