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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e7d21a23e6ff36da776bfb32e5998a3827d9c8e52eb67e1a9def887005e68f' 
  AND token = 'RSeXcn9yMVW9dBlXiiKLYbOU8jTRHM6n5Ajjm/aL9CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}