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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3717ad9e68974a565a565a69a9f75f9d5be4b22b338f2348b4d236579f73f5b' 
  AND token = 'Tx1hv6UXlNz2NTMTcYhZA8thAFXK104GedkJK2nuVtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}