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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d65cfe6b19aa90863f239d5f4e3a92eaec7c248fe63e13e4a0ab2f982a564cd' 
  AND token = 'iB0dVvB1q/fBV5qbTJn+RcRTmlB3eoukmxz4UlJ1UJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}