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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2f0c31cab15bd4d4f92e1e9598233eeea5a872d5c0b441c2e3781c111d6f79' 
  AND token = 'w9l8iLnPVlOdF4yLPzZQ2IOHdwyOEMeZWkq2s6veTfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}