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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08649ba1c254bcdd5a62ae907ece2d2e6ca31d1a5eea3029b5fed778d6e94707' 
  AND token = '8961WOb6tvj7CGTRMp2R7b1lRgRnt6TWaEBwjiFAxpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}