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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b557695d4b485158de043d7ae78e19835bec98a0251a7534263265ea2d38142b' 
  AND token = 'sDTCm9PInd9rWk+CaoUh6sV/R78ThdBu0B17CfOWcHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}