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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8a13005e5a0d21e53fc29e060fdba21bc7486a0f2383c51e4c66d03b4d793b' 
  AND token = '+UhTpgI3SKNUUp/PenfXlw7b1cS2a6qf4hF6QR/gBK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}