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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd571d634c1024875082adaf5737b3f503852951053e4e53e78c966dbcb846f45' 
  AND token = 'Z0ZtGekJaWTLVD/kXXjLdyDKbKRVELp4/WMslRqq3pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}