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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279ce626d986d1a98437cef0dd6b6fe0c616a0af54f6141d56ceb9909d149b80' 
  AND token = 'aojRuISG1x9hLBjmy9u4HZoNQJXdJYRB1iRe4OaPfHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}