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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a159ce7217561ef3fc8ebf5c05d685e111fcd39e8000527a7040367b84240fe4' 
  AND token = 'Hbt1x77pg+q7iq94ArR9zQBCQSxeNfjqmaeXUIe+C0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}