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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353a90b27607bd4cf5f802ab610b103ab1b58e4ecec15230480865cab6e7f69f' 
  AND token = 'Mi0sp8kYKzhmAvdlJtC3555vxyROoTsxrvNa5/UvOXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}