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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27adc6929812d133a774bf530e3d647a30e01c4641304a46e2b19ed6c6e2d13' 
  AND token = '01k/0lWx2NvYA45+jxQc+W9NsGAmTYmuzsELrG8JH60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}