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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d354f69365c835203a4718c622e56ddf3f9d1de35eccb8df8c99015c0ab9a4' 
  AND token = 'VMr/kMhgAx/iSlq4Arx6qY9zyPE0LVPTSxAmlw278hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}