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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b729d0c70be7e9ca7af740faa62c5684be4c9f38ac5ca6e1ed189efdc5f18b35' 
  AND token = '4/4NqMN/b0BHcrpvvXLMKsdNQifT546lg6H7ifcXOvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}