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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d459757053fbbdf42e866f7d09cbd1eeaaadb7f4cf1d1e83674ac20c8cc279' 
  AND token = 'mDFLv79R8doCw+ZXWAgoZoPjCHEIW4go/FAs/gIm7Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}