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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce03d6c5fcd9c2c9854406e3e250501fe1e0c22ed5dcff48d6379664e17ba8d8' 
  AND token = 'I+6cIZ26iHr3FjLfgBRYmM5mwRgh7IU50OgXlrf7kyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}