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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8010b4ef5e012d2a3a5c51f37b50b063b5a1e1d29e3191cfcbd4e9a87a72f2fd' 
  AND token = 'zD/lsNVcS/HCcwibu84V/DjGgyzst6IrtW3LaOLgnFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}