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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '584574ce8e7cb6b39021a7e1b215be7a63220e314d1ccc3fcfea1329e1e7c1e8' 
  AND token = 'a3I4siVO5kYVByP4lqtffvH7zgYEYHawjh1SkAmDrk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}