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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c012168cd0cfebcd3cb11e83297c53cb244e1c2d2f8118f7ccf0644cb3750e' 
  AND token = 'LgqQAjTS3wsNu1+lMGoSxvR+DvtLtbk4rvRQzvZPh1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}