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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e7aa1c58e0fb87585f81888b439292bfd29c4de2ddbbb9cb089c0a7efced284' 
  AND token = 'K4Y+ST3FgOK8xiQnZdE3554O/3yY9F8QFkyf1zaqJko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}