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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ee4515df0e2b4e92cd47e94a1bc22dbb63957627297bad9371fb0d0dc960c4' 
  AND token = 'nY8yWQPrLtJ0YReHxMLCjFLWlo1XnfnsVmyMMPbuz6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}