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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3646de3d9e3c6f1ae70d50c2040a9ebcb5b52cad6cfd375ef1171ea6dc599c5b' 
  AND token = 'IxuVT8dMMmaAcvoJGk0dRRdODmMz1HWJS3NKHBeePfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}