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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5fc25353fd6a579f70ab5ee6731f459743eb13cf8f1baf307e04a7c2439d77' 
  AND token = 'kTPnmKUWAANxxf+350dWOKGUPciSVqRZK6H7vY1gUTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}