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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b61d2591fbb35efa38825c688c4ea3b7add5be0dc23e8b1f85f905de4892970' 
  AND token = 'Iju6yMg7AkpGEFiMMaBZU3E6pGOgOmILBV4wM1gAwks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}