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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f576ce384491249082003c7c993e25deac190ea77dd7449603e66dd2ce7f944' 
  AND token = 'OlzMaaZWZuawy/PnERiAbgU91/2rTzrl0PM/6cU5AHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}