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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387507230ec7a63a52b3a0fd8602167fe5b69e2c8ebf03ed6d7466d1712ec4ae' 
  AND token = 'uZ0gnZDbVThbISRBqVq0PS1/32VsTpnE5zAYXeLmFQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}