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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6442dfde2c147433efc0cdda33e00f3b026667e18719a603552291f9d6199d88' 
  AND token = '7NHuUShOUcUcaAbHg1UOFBD6VZjlqStpTW+eNDD/X3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}