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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af38890c2c7b9e4bf5a1a920bc0b037ca46e21a5b8cea26261880e87319fbc7' 
  AND token = 'QW0Do2Utgy0LfAnx2v69Aox2ykpNEoKOPNx0aRJ/1d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}