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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e896a8fa3e572c72c7664050b1249881e03854e017340e842609a087d0dd53' 
  AND token = 'MHriH2CmqjYm+a6SVOXGGsaN8rKRoW5ImRvCXul36Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}