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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17180fd2d381b1f59d9654c50f69e74667d2a686fbb0b9bee4a5ddbfe8c74a8c' 
  AND token = 'brDyeFKJlRcM9wsZ8Bac13xHEifo56BEUI3hR4G+1LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}