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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd097086106be726408e512226814c186cb74856c978d0dd94d077b18cb2c9b4' 
  AND token = '4LfOtUNqmjkSyTwjfmwrSpNd3lV56X6Fi3VMcH9Dfmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}