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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3390613dd113e296d59f40d946a15e3c3c1b1506713fc65a80de92020a2772ac' 
  AND token = 'MkpoJu5dARLjsPoG9SKvulcsSt+/LgeNUGavlSu0WmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}