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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eca73c713202458367dbec287f64fe2d900867fe373005eff1cd4a208a48390' 
  AND token = '1p9XIMCKd8WX3malLv6KNwsdEd30l7DEjysST2knW7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}