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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41cb8192ef3b63e02d2ab08fbe35edd334b05f37cd469926e836872e323463e4' 
  AND token = 'cyxLuZz5gpSbizEW31VVjm+xJWrV1Uw7Pdh+F96EzIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}