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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b81a062833f0d08e4eb22e2cc034a8388c148ccc417cd7870cabdf998804e9' 
  AND token = 'W5FvPVL+AWawk7S8lL62mbU0/G5MzPvP5pPs/AtkrV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}