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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd40378d07cbf6fc05da1e2a38f1d051199ca51a95af00cfafac61e2f846acb18' 
  AND token = 'YhcXkY55LkIHvoMYD/01RGS3FapfgsxBPR2DOh/ZRp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}