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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a72aa7fe8590184a745dd33e55eefec177f8ba4c7b2542f7e329d17845a93f' 
  AND token = 'yIKYJYYX2tYiQVm2X+VSKV6fuT1OmErXaReLtS61cvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}