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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e845e23b8deb0d8f0c425933b32d2613c92789375260263f4d533167c1ff14' 
  AND token = '5yYac2D57nB61G3F428n6gcks2f1vw37rt5pTsmCEqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}