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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b487ce79c370ddbd72e0d9884af21fa8cb194b0cbfaa255b33c1b8a719c62493' 
  AND token = 'vVa8Of9vPQ+Mo0+lwN8sMLDmgkT4w4IepyR2fKJmp50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}