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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45efc03302201d57f9e429c7f4fe38bc5c4f6d4c1969e8209906cbf680379a4' 
  AND token = 'WucYGL7zP3/GoB1YWk3D4sGDxuHQ59anJ4tI1BQIogo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}