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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361d1dd44a3a3c446eab669f6e0ad86e4b4eb645c17ad696629582c39e39e288' 
  AND token = '6jFbi1xP6Y1fCrMLGjGiAfiS8pzdOR7asmRTu0/7kdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}