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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f57dc9152c023fad8f3f05a8a58994b21d26fb82c32cbde265f204d774e79ee7' 
  AND token = 'Sxdp/2SRRN3RBLns+noUFb62QX2pCMjC65hoUhL/WTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}