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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2cb94dc4b57c1ff12c1250b834340fdc8896ed6d8d5d05ea0fe4e3e5fce214' 
  AND token = 'f5F+NmHo+ZSR5eiyk9tuIkvMyJTyyqlPl/m+1KDiHuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}