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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9da6ef0fe46fb1b1ce11454dffcbe915479c4ecd64d56bf531be89e18e680594' 
  AND token = 'QRtHHqIbz97xL/D9BWs81LXC3SDWxNgVV2MygWt9pJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}