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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d327d957ad1e85e0b03754eb36155446b8c8bb8983c2b9d36952d7762f8c02' 
  AND token = 'lcjBwXB1psl0ekJUNapYRiSqFoR7s7F5S4vlzA4YiAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}