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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea73feb6be8aa0e036157e2f413d1906e94cdee2dea201fe8ed581f41757f685' 
  AND token = 'TYRsbcRjqw5t7CXFJJQZOPmE8wAnotaKYF5WMD0BqDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}